A nurse holds vials of AstraZeneca vaccine against COVID-19 during a vaccination campaign at WiZink indoor arena in Madrid, Spain, Friday, April 9, 2021. THE CANADIAN PRESS/AP/Manu Fernandez

A nurse holds vials of AstraZeneca vaccine against COVID-19 during a vaccination campaign at WiZink indoor arena in Madrid, Spain, Friday, April 9, 2021. THE CANADIAN PRESS/AP/Manu Fernandez

Several provinces lower age eligibility for AstraZeneca: at look at the vaccine

Ontario, Manitoba and Alberta are decreasing the age range from the recommended 55+ NACI set

Several provinces are lowering their minimum age requirement for the Oxford-AstraZeneca vaccine, allowing those 40-and-older to receive the jab as unruly spread of COVID-19 continues in their jurisdictions.

Ontario, Manitoba and Alberta are decreasing the age range from the recommended 55+ that the National Advisory Committee on Immunization set last month.

The NACI guidelines came about as Canada and other countries investigated possible links to rare instances of blood clots seen in a small minority of AstraZeneca recipients.

Those events continue to be an exceedingly rare side effect of the vaccine, with Canada reporting twocases out of more than 700,000 doses administered.

Here’s what we know about the AstraZeneca vaccine:

WHO IS ELIGIBLE TO GET IT?

As of Tuesday, people 40 years of age and older will be able to get the AstraZeneca jab in Ontario and Alberta. Manitoba said Monday that it, too, was offering the vaccine to those over age 40.

Health Canada had allowed the use of the vaccine for those 18 and up when it approved AstraZeneca in February, an authorization that has not changed.

Health Minister Patty Hajdu said in a press conference Sunday that provinces and territories were “free to use AstraZeneca in any aged population over 18.”

NACI had not updated its minimum age guidance for AstraZeneca as of Monday morning.

Ontario, Manitoba and Alberta’s move to a lower age range comes amid mounting pressure to expand eligibility as a third wave devastates parts of the country.

Alberta had the highest rate of active COVID-19 cases in Canada as of Sunday, while Ontario had reported an average of more than 4,300 new daily cases over the past week.

Concern around the rare clotting events has led to some hesitancy around AstraZeneca, with many eligible residents opting to wait for a jab from Pfizer-BioNTech or Moderna instead. As the COVID situation worsens in parts of the country, however, experts advise against waiting for another vaccine.

WHAT DO WE KNOW ABOUT THE BLOOD CLOT ISSUE?

The European Medicines Agency said earlier this month it found a possible link to very rare cases of unusual blood clots with low platelet counts in AstraZeneca recipients, usually happening within two weeks of getting the shot.

The global frequency of the blood clot disorder, known as vaccine-induced immune thrombotic thrombocytopenia or VITT, has been estimated at about one case in 100,000 to 250,000 doses.

Data published in the online journal Science last week said there were at least 222 suspected cases reported in Europe — out of 34 million people who received their first dose. More than 30 people have died.

Experts say the risk of developing blood clots due to COVID-19 is much higher, and they encouragepeople to accept the first vaccine they’re offered.

The EMA says symptoms to watch for include: shortness of breath, chest pain, swelling in the leg, persistent abdominal pain, persistent headaches and blurred vision or tiny blood spots under the skin beyond the injection site. The clotting issue has been treatable when caught early.

VIDEO: ‘Extremely, extremely rare’ blood clots ‘may be linked’ to AstraZeneca, Health Canada says

HOW EFFECTIVE IS ASTRAZENECA IN PREVENTING COVID INFECTIONS?

Data from clinical trials showed AstraZeneca was 62 per cent effective in preventing COVID-19 infections, but it prevented death and hospitalization in all participants who got the virus after receiving the vaccine.

Efficacy was a major talking point when AstraZeneca was first approved, with some comparing it to the 95 per cent efficacy shown in vaccine trials from Pfizer and Moderna.

But experts have stressed that all the authorized vaccines offer excellent protection against severe disease, hospitalization and death.

Real-world data may also suggest the efficacy of AstraZeneca’s vaccine increases over a longer time interval between the first and second shot. Clinical trials used a four-week span between doses but some countries have been delaying second doses by several weeks. In Canada, many provinces have opted to delay the second dose by four months.

HOW DOES THE VACCINE WORK?

All of the approved COVID-19 vaccines train the body to recognize the spike protein that coats the outer surface of the coronavirus.

AstraZeneca — a non-replicating viral vector vaccine — uses a harmless version of a cold virus as a vessel to give our cells the instructions they need to make the coronavirus’s spike protein.

The immune system recognizes the protein and makes antibodies, which then allow us to fend off attack if exposed in the future.

Experts say it takes a couple of weeks for the body to build up some level of immunity with any of the vaccines.

Some may see outward signs of an immediate immune response to the inoculation — the body’s way of preparing for what it perceives as an attack by the virus. This can cause side effects usually seen with other vaccines, including pain at the injection site, redness, swelling and even fever, but experts say that means the vaccine is working.

WHAT ARE THE ADVANTAGES TO THIS VACCINE?

The AstraZeneca vaccine can be shipped and stored at regular refrigerator temperature, unlike those by Pfizer-BioNTech and Moderna, which need colder storage temperatures.

That’s why they’ve been primarily used in pharmacies across the country, rather than large vaccine clinics.

From a global vaccination standpoint, the low cost of AstraZeneca’s vaccine — about US$4 per dose — gives it another advantage. AstraZeneca, which says it aims to manufacture up to three billion doses in 2021, has pledged to make their product available at cost around the world until at least July.

The Canadian Press


Like us on Facebook and follow us on Twitter.

Coronavirusvaccines

Just Posted

The mighty Fraser during freshet on May 2, 2021 at Island 22 Regional Park. A new B.C. coalition representing 25 organizations, and 273,000 people, is calling on B.C. to reverse decades of wildlife and habitat declines. (Jennifer Feinberg/ The Chilliwack Progress)
Coalition calls on B.C. to invest in wildlife stewardship and habitat protection

Representing 25 organizations, and 273,000 people, they seek to reverse decades of declines

Terry Driver as he looked around the time of the killing of Tanya Smith and the attempted murder of Misty Cockerill in Abbotsford in October 1995. No current photos are available of Driver.
‘Abbotsford Killer’ Terry Driver denied parole, deemed ‘high risk’ to re-offend

Driver murdered Tanya Smith, 16, and seriously injured Misty Cockerill, 15, in 1995

Boats in the Fraser River launched from Barrowtown and Ft. Langley on May 12 to search for the missing fisherman. (Steve Simpson)
Boats search the Fraser River for missing Abbotsford fisherman

Anyone with ‘a boat, time, or a drone’ to help bring Damian Dutrisac home was asked to help

Mina Shahsavar is a fourth-year student in the bachelor of science in nursing program at University of the Fraser Valley and is an employed student nurse at Abbotsford Regional Hospital. (Submitted photo)
Nursing student in Abbotsford plans for career in critical care

Mina Shahsavar inspired during hospital stays as a child

The Canadian Forensic Health Corporation, made up of (left to right) Kirstin Simpson, Adrienne Fershau, Tiffany Kafka, Susan Short and Cole Bruce, are changing the game for the forensic nurse occupation. (Submitted)
Abbotsford nurses create Canadian Forensic Health Corporation

Tiffany Kafka, Susan Short, Kirstin Simpson, Cole Bruce and Adrienne Fershau teaching new generation

B.C. Labour Minister Harry Bains in the B.C. legislature, May 13, 2019. (Hansard TV)
VIDEO: B.C. to provide 3 days of sick pay for COVID-19 absences

Province will support employers on cost, labour minister says

Capt. Arpit Mahajan of the Canadian Forces Snowbirds - Snowbirds 2 - shows off his ‘Jenn Book’ dedicated to Capt. Jennifer Casey. Zoom screenshot
Homecoming for B.C.-raised Snowbirds pilot training in the province

Capt. Arpit Mahajan flies Snowbird 2 in his first year as a solo pilot with the team

BC Housing minister David Eby. (THE CANADIAN PRESS/Chad Hipolito)
Eby jabs back against Penticton mayor’s ad urging BC Premier to intervene in shelter dispute

Eby writes that Penticton’s ‘serious’ social issues won’t improve under leadership of the mayor

What3words was first created in the U.K. in 2013 and is credited to saving the lives of outdoor enthusiasts around the world. (Contributed)
‘This is a life saving tool’: App helps paramedics find capsized canoeists near Revelstoke

What3words pinpoints the person’s phone location to a three-meter range

Provincial health officer Dr. Bonnie Henry updates B.C.’s COVID-19 situation at the B.C. legislature, April 29, 2021. (B.C. government)
B.C.’s COVID-19 rate creeps up again, 600 new cases Wednesday

One more death, 423 people in hospital with virus

B.C. Agriculture Minister Lana Popham takes questions in the B.C. legislature in 2017. (Hansard TV)
UPDATE: B.C. will fund another year of fresh fruit, vegetables, milk in schools

John Horgan government working on school meal program

Surrey RCMP is releasing sketches of a suspect in an “indecent act” at the Coyote Creek Elementary playground on April 30, 2021. Police said the suspect was clean-shaven “during some interactions” and on “other occasions had stubble outlining a goatee and mustache.” (Images: Surrey RCMP handout)
Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

Most Read